Alright, well, I downloaded the official binaries and data, and the program won't start. The screen goes black, then my computer crashes. I recently upgraded my graphics card from a GeForce 9500 to a GTX 260, but I am pretty sure I ran Glest on my GTX. Does Glest have any problems with this particular video card? One thing I am not sure I ran Glest under the 190.53 nvidia drivers. I'll update to the very newest drivers, and see if that helps anything.
EDIT: Bah, I installed the new drivers (195.36.08), and the exact same thing happens when I start up the program.