Excuse my lateness. My two bits:
Yes, the screen should be disabled, but, not on the first run. You see, I never would have even come to this site, and thus found the forums, if I wasn't reminded of the web site when I played the game (yes, it's surprisingly easy to download a game, without actually even looking at anything else on the site). After that, I'm with Chupa in giving an option, preferably in the options menu, for toggling whether or not to show the intro. This could persist even when a real cutscene video is added (albeit, that video would have to be very high quality and probably entirely rendered in a video editor, not consisting of ingame clips. Something similar to civilization 4 comes to mind (though not necessarily such quality). Of course, then there's the problem with playing a video, as videos are huge, and the format that most games (including aforementioned civilization 4) is Bink, which is commercial, leaving us with fewer choices that won't create a massive filesize.