I played a couple r4618 games today, some with Typedef (Linux 3.x-64), some with Nig (Windows 7-64). There were no checksum mismatches. However, we had serious problems with FPS dropping remarkably after the first third/half of the game. Both ends were then constantly playing at 1-3 FPS, i.e. unplayable. This happens whether or not we are using CRC checksumming, with different techtrees, different maps, different AI settings, different tilesets, and whether Nig or I were hosting.
Yesterday I took part in three games where this wasn't a problem, and where no mismatches occured either. But those were only 2 player games, like today. So it may be too early to tell whether everything is fixed. And large games are not possible with the current slowdowns.